Cancer immunology research
Pan-cancer single-cell RNA sequencing analysis refines multi-origin monocyte and macrophage lineages.
Truc Do Thanh Nguyen, Andrew J Lee, Hyun Jung Park, Nameeta Shah, Bayrta Mandzhieva, Dong-Sup Lee, Inkyung Jung, Woong-Yang Park
Published: 202510.1158/2326-6066.CIR-24-1255
Abstract
Tumor-associated macrophages (TAMs) play crucial and important role in cancer dynamics by affecting homeostasis, immunosuppression, and angiogenesis within the tumor microenvironment. Using single-cell transcriptomics, we constructed a comprehensive…
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