Cancer discovery
Base Editing Might Be Key to CAR T-cell Therapy.
Published: 202610.1158/2159-8290.CD-NW2026-0007
Abstract
Researchers used a unique base-editing strategy to engineer chimeric-antigen receptor (CAR) T cells that engraft in the host and remain invisible to remaining antibody drugs. Of the 11 patients with T-cell acute lymphoblastic leukemia who received th…
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