Clinical cancer research : an official journal of the American Association for Cancer Research
Improving a Plasma Biomarker Panel for Early Detection of Pancreatic Ductal Adenocarcinoma with Aminopeptidase N (ANPEP) and Polymeric Immunoglobin Receptor (PIGR).
Brianna M Krusen, Phyllis A Gimotty, Greg Donahue, Jacob E Till, Melinda Yin, Erin E Carlson, William R Bamlet, Erica L Carpenter, Shounak Majumder, Ann L Oberg, Kenneth S Zaret
Published: 202610.1158/1078-0432.CCR-25-3297
Abstract
PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) is typically detected too late for useful therapeutic interventions; hence, we sought blood biomarkers to detect early-stage disease. EXPERIMENTAL DESIGN: Using mass spectrometry and ELISA on plasma po…
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