Clinical cancer research : an official journal of the American Association for Cancer Research
Excessive dissection of non-metastatic tumor-draining lymph nodes impairs immunotherapy efficacy in recurrent biliary tract cancer.
Yin Long, Botao An, Qi Li, Yan Geng, Yang Zhou, Zhimin Geng, Sheng Tai, Yongyi Zeng, Jinhong Chen, Yajin Chen, Lei Zhang
Published: 202510.1158/1078-0432.CCR-25-3296
Abstract
PURPOSE: Non-metastatic tumor-draining lymph nodes (TDLNs-) are central to initiating and sustaining antitumor immunity. The impact of their surgical removal on immunotherapy efficacy in recurrent biliary tract cancer (BTC) remains unclear. We invest…
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