Clinical cancer research : an official journal of the American Association for Cancer Research
Integrative Clinical and Molecular Evaluation of Renal Cell Carcinoma with Merlin Protein Deficiency and Biallelic Loss of NF2.
Emre Yekedüz, Weiwei Bian, Stephanie E Siegmund, Marc Machaalani, Jad El Masri, Mustafa Saleh, Eddy Saad, Liliana Ascione, Razane El Hajj Chehade, Clara Steiner, Pablo Moura Barrios, Stephanie A Berg, Bradley McGregor, Charlene Mantia, Praful Ravi
Published: 202610.1158/1078-0432.CCR-25-2871
Abstract
PURPOSE: In renal cell carcinoma (RCC), loss of the NF2 tumor suppressor gene encoding the merlin protein is associated with aggressive clinical behavior. However, data regarding the clinical course and additional molecular features in the context of…
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