Clinical cancer research : an official journal of the American Association for Cancer Research
Accelerating Drug Development in Hormone-Naïve Prostate Cancer Through Multi-Modal Therapy Strategies: The MetaCURE Phase 2 Randomized Clinical Trial.
Deaglan McHugh, Matthew Dallos, Min Yuen Teo, Sean M McBride, Anuradha Gopalan, Andrea Arfe, Christopher D Gaffney, Mehak Amjed, Patrick J McCann, Hannah Benoliel, Karen A Autio, Alvin C Goh, Kevin Derudder, Catherine J Ryan, Russell Z Szmulewitz
Published: 202510.1158/1078-0432.CCR-25-2679
Abstract
PURPOSE: To accelerate prostate cancer drug development and identification of promising therapies, we aimed to establish a framework for a multi-modal therapy (MMT) approach using intermediate endpoints of efficacy due to treatment. METHODS: In the M…
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