Clinical cancer research : an official journal of the American Association for Cancer Research
FET-rearranged Myoepithelial Tumors are Clinically Heterogeneous and Epigenetically Distinct from PLAG1-rearranged Adnexal and Salivary Gland Myoepithelial Tumors.
Michael Michal, Faizan Malik, Boulos Mansour, Travis Hattery, Carina A Dehner, Petr Martinek, Veronika Hájková, Tomáš Vaněček, John S A Chrisinger, Isidro Machado, Natálie Klubíčková, Vaiyapuri P Sumathi, Tony Ng, Laura Warmke, Ming Liang Oon
Published: 202510.1158/1078-0432.CCR-25-2426
Abstract
PURPOSE: Fusion-positive myoepithelial tumors (MET) are clinicopathologically heterogeneous and variably termed mixed tumors and myoepithelial carcinomas. Since FET-rearranged MET lack ductal/epithelial differentiation, we test whether FET-rearranged…
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