Cancer research
Microglia Display Heterogeneous Initial Responses to Disseminated Tumor Cells.
Takahiro Tsuji, Haruka Hirose, Daisuke Sugiyama, Mariko Shindo, Rahadian Yudo Hartantyo, Yutaro Saito, Tsuyako Tatematsu, Shouta Sugio, Makoto Sanbo, Masumi Hirabayashi, Yasuhiro Kojima, Jun Koseki, Kazutaka Hosoya, Hiroshi Yoshida, Tatsuya Ogimoto
Published: 202510.1158/0008-5472.CAN-25-3425
Abstract
Brain metastases are frequent and often lethal complications of advanced cancers. Microglia, resident immune cells of the brain, are known to exert both anti-tumor and pro-tumor functions in late-stage metastases; however, their response during the i…
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