Cancer researchEpendymomaHumansTranscriptomeSupratentorial NeoplasmsFemale
Integrated Single-Nucleus and Spatial Transcriptomics Elucidate Heterogeneity and Hypoxia-Driven Organization of Supratentorial Ependymoma.
Erik Schüftan, I-Na Lu, Flavia W de Faria, Clara Inserte, Claudia Rössig, Julia Bothe, Adrienn Bagosi, Stephan Tippelt, Tobias Blau, Camelia Monoranu, Lea Altendorf, Dorothee C Spille, Ann-Katrin Bruns, Angela Brentrup, Walter Stummer
Published: 202610.1158/0008-5472.CAN-25-2694
Abstract
Supratentorial ependymomas (ST-EPN) are often life-threatening brain tumors that are characterized by significant molecular heterogeneity. Hypoxia contributes to this heterogeneity, but the extent and nature of this relationship remain unclear. This…
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