Cancer research
Loss of JAK1 Function Causes G2/M Cell Cycle Defects Vulnerable to KIF18A Inhibition.
Vanessa M Kelley, Marta Baro, William E Gasperi, Nicholas R Ader, Hannah Lea, Hojin Lee, Chatchai Phoomak, Lilian Kabeche, Megan C King, Joseph N Contessa
Published: 202610.1158/0008-5472.CAN-25-1423
Abstract
Therapeutic resistance to DNA damage is a significant challenge in oncology. To gain insight into biological mechanisms that cause DNA damage resistance and to inform strategies for achieving synergy with therapeutic radiation, we performed parallel…
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