Disseminated Cutaneous, Osteoarticular, and Tubulointerstitial Sporotrichosis in an Immunosenescent and Diabetic Host: A Case Report.

Introduction: Disseminated sporotrichosis is an uncommon presentation of this infectious disease, primarily observed in immunocompromised patients. Here, we present a case of disseminated sporotrichosis occurring in an immunosenescent patient. Case presentation: An 81-year-old man presented to our clinic with skin ulcers in the scalp, back, right arm, and both legs, knee arthritis, and acute kidney injury. After skin biopsy and synovial fluid analysis, the diagnosis of disseminated sporotrichosis was made using fungal culture and in-house PCR. The only factor that favored immunocompromise was immunosenescence. Conclusion: This case of disseminated sporotrichosis highlights its rare occurrence in a patient with controlled diabetes and immunosenescence. Advanced diagnostics confirmed Sporothrix schenckii as the causative agent, and itraconazole treatment led to significant improvement.