American journal of physiology. Renal physiology
Citrate modulates calciprotein particle formation and composition.
Guido de La Roij, Robin H M van der Meijden, Luco Rutten, Charlotte A Hoogstraaten, Maureen Hinnen, Stan Martens, Joost G J Hoenderop, Jeroen H F de Baaij
Published: 202610.1152/ajprenal.00391.2025
Abstract
Chronic kidney disease (CKD) is a risk factor for cardiovascular disease (CVD), partly due to phosphate-induced vascular calcification. Fetuin-A stabilizes calcium-phosphate complexes into calciprotein particles (CPPs), preventing precipitation, but…
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