American journal of physiology. Renal physiologyAnimalsFemaleObesityMaleBlood Pressure
Obesity enhances salt-sensitivity of blood pressure, independent of skin electrolytes, and more in female than in male ZSF1 rats.
Isabel T N Nguyen, Olav Tenstad, Anne-Maj Samuelsson, Helge Wiig, Ewout J Hoorn, Marianne C Verhaar, Jaap A Joles
Published: 202610.1152/ajprenal.00335.2025
Abstract
Obesity and sex influence the salt-sensitivity of blood pressure, but it is unknown whether this also affects tissue electrolyte accumulation. We hypothesized that obese female rats exhibit greater salt-sensitivity of blood pressure with higher nonos…
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