American journal of physiology. Renal physiologyAnimalsReceptorAngiotensinType 2Natriuresis
Protein phosphatase 2A subunit B55 alpha is required for angiotensin type 2 receptor elicited natriuresis.
John J Gildea, Jie Li, Nancy L Howell, Brandon A Kemp, Mark R Conaway, David L Brautigan, Robert M Carey, Susanna R Keller
Published: 202610.1152/ajprenal.00256.2025
Abstract
Angiotensin type 2 receptor (AT2R) activation promotes natriuresis, thereby contributing to sodium balance and blood pressure regulation. In this study, we explored a novel intermediate in AT2R signaling, protein phosphatase 2A (PP2A) regulatory subu…
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