American journal of physiology. Regulatory, integrative and comparative physiology
Peripheral blood mononuclear cell mitochondrial bioenergetics are related to vascular endothelial function in young and older adults.
S Tony Wolf, James F Bangle, William E Jennings, Georgia R Albino, Melissa Gorejena, Briana L Clary, Junwon Heo, Jarrod A Call
Published: 202610.1152/ajpregu.00262.2025
Abstract
The use of peripheral blood mononuclear cells (PBMCs) in cardiovascular research is increasingly common. However, little is known regarding potential age-related changes in mitochondrial bioenergetics and oxidative stress in PBMCs, or whether such ch…
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