American journal of physiology. Lung cellular and molecular physiology
Early Detection of Small Airway Dysfunction in Smokers and People with COPD via Forced Oscillation Technique and its Association with Biomarkers: a Pilot Study.
Prem Bhattarai, Maksim Grigorenko, Wenying Lu, Collin Chia, Steve Myers, Sukhwinder Singh Sohal, Andrew Williams
Published: 202610.1152/ajplung.00155.2025
Abstract
Background: Early airflow changes associated with tobacco smoking often occur without observable obstruction or symptoms. Spirometry, the gold standard, has limitations in detecting early disease highlighting the need for sensitive diagnostic methods…
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