American journal of physiology. Heart and circulatory physiologyAnimalsMaleFemaleMyocytesCardiac
Excitation-contraction coupling, cardiomyocyte electrophysiology, and transcriptome profiles in two HFpEF murine models: etiology and sex-dependent differences.
Bence Hegyi, Logan R J Bailey, Juliana Mira Hernandez, Christopher Y Ko, Erin Y Shen, Julie Bossuyt, Jennifer M Davis, Donald M Bers
Published: 202610.1152/ajpheart.00227.2025
Abstract
Heart failure (HF) with preserved ejection fraction (HFpEF) comprises heterogeneous clinical phenotypes and variable comorbidities. Recent two-hit translational animal models, including the hypertensive, nitrosative-stressed mice fed with high-fat di…
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