American journal of physiology. Endocrinology and metabolism
Impact of AKR1C2 and AKR1C3 single nucleotide polymorphism rs28571848 in adipose tissues of individuals with severe obesity.
Giada Ostinelli, Alan Ramalho, Marie-Fréderiqu Gauthier, François Julien, Laurent Biertho, Marie-Claude Vohl, André Tchernof
Published: 202610.1152/ajpendo.00512.2024
Abstract
Background: Adipose tissue androgen turnover, dictated at least in part by the enzymes AKR1C2 and AKR1C3, has been linked to abdominal obesity. Recently, we investigated a single-nucleotide polymorphism (SNP) named rs28571858, that might increase AKR…
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