American journal of physiology. Endocrinology and metabolismAnimalsUncoupling Protein 1MiceKnockoutTransgenic
Uncoupling protein 1 in nonadipose tissue.
Xi Hu, Donghua Hu, Kun Chen, Mengjiao Xu, Yaying Chen, Lisheng Fu, Deping Wu, Xinkai Qu, Jiqiu Wang, Chengchao Ruan, Junfeng Cai, Kailei Shi, Maoqing Ye
Published: 202610.1152/ajpendo.00260.2025
Abstract
Uncoupling protein 1 (UCP1), a mitochondrial protein traditionally regarded as exclusive to thermogenic adipocytes, and Ucp1-promoter-driven Cre is widely used in gene manipulation in thermogenic adipocytes. However, new evidence suggests that Ucp1-p…
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