American journal of physiology. Cell physiologyAnimalsCOVID-19Hypoxia-Inducible Factor 1alpha SubunitPulmonary Fibrosis
Decoding fibrosis in nonresolvable COVID-19: a role for myeloid-specific HIF1A deletion.
Kemly Philip, Hannah P Thompson, Scott D Collum, Isabella Lefebvre, Bindu Akkanti, Bihong Zhao, Rahat Hussain, Manish Patel, Michael R Blackburn, Tingting W Mills, Harry Karmouty-Quintana
Published: 202510.1152/ajpcell.00060.2025
Abstract
A complication of viral lung infections is the development of pulmonary fibrosis. This phenomenon is most evident in patients with COVID-19, where in its most aggressive form patients developed nonresolvable (NR) COVID-19 requiring lung transplantati…
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