Thorax
Efficacy of fentanyl buccal tablet and morphine for exertional dyspnoea in patients with cancer: a double-blind, placebo-controlled, randomised clinical trial.
David Hui, Soraira Pacheco, Linh Nguyen, Kristofer Jennings, Vera de la Cruz, Penny Stanton, Raul Laureano, Amy Ontai, Donald Mahler, Eduardo Bruera
Published: 202510.1136/thorax-2025-222970
Abstract
INTRODUCTION: Exertional dyspnoea is highly debilitating. Previous single-dose studies found that prophylactic administration of fentanyl buccal tablet (FBT) improved exertional dyspnoea. In this randomised trial, we compared daily use of prophylacti…
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