Stroke and vascular neurology
Loberamisal injection for the treatment of acute ischaemic stroke: a multicentre, randomised, double-blind, placebo-controlled phase II clinical trial.
Baoyu Feng, Hao Li, Shuhong Xu, Jian Li, Yilong Wang, Xingquan Zhao, Yan Wei, Xiaohua Xiao, Suping Wang, Yongjun Wang, Shuya Li
Published: 202510.1136/svn-2025-004581
Abstract
BACKGROUND AND AIMS: Loberamisal is a small-molecule agent that inhibits the nNOS-postsynaptic density protein 95 coupling and enhances α2-containing γ-aminobutyric acid type A receptor, which has been shown effective in animal studies. This trial ai…
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