Stroke and vascular neurology
Reduced endothelial TAK1 impairs vascular integrity in cerebral small vessel disease via the RIPK1-MLKL signalling pathway.
Jing Yang, Chi Xiao, Ming Yi, Kun Zhou, Xiangming Xu, Yuhua Fan
Published: 202510.1136/svn-2025-004469
Abstract
BACKGROUND: Hypertension stands as a major modifiable risk factor for cerebral small vessel disease (CSVD), driving pathological cerebrovascular rarefaction and blood-brain barrier (BBB) compromise through endothelial dysfunction and death. However,…
Preview only. Read the full abstract at the source