Regional anesthesia and pain medicine
Effects of peripheral nerve block adjuvants with and without local anesthetic on ex vivo rodent nerve A-alpha/beta, A-delta, and C fiber activity.
Micaela Quinn Dugan, Mary Dubus, Alyssa Mae Flippen, Mark Rainier Catapusan, Zara Thomas, Namrata Sangwan, M Klukinov, Cholawat Pacharinsak, David Yeomans, Thomas Anthony Anderson
Published: 202610.1136/rapm-2025-106955
Abstract
INTRODUCTION: Preclinical and clinical studies have shown enhanced analgesia when some adjuvant medications are combined with local anesthetics during peripheral nerve (PN) blockade. However, the effects of many adjuvants on individual PN fibers, tha…
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