Journal for immunotherapy of cancerCarcinomaHepatocellularHumansLiver NeoplasmsLung Neoplasms
Tumor neoantigen gene C7orf50 remodels the immune microenvironment by recruiting tumor-associated macrophages to promote hepatocellular carcinoma progression and lung metastasis.
Jia Li, Xinming Ye, Sheng Su, Zhiqiang Hu, Changzhou Chen, Yu Gong, Zehuan Li, Feng Qi, Hecheng Li, Li Mao, Xiaowu Huang
Published: 202610.1136/jitc-2025-011997
Abstract
BACKGROUND: Hepatocellular carcinoma (HCC) is a global health challenge with high mortality rates, particularly in patients with advanced disease and lung metastasis. T-cell receptor (TCR)-T cell therapy based on specific neoantigens, is an emerging…
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