Gut
Twenty-four-week anti-PD-1 antibody regimen promoted HBsAg reduction and concurrently enhanced HBV-specific T cell responses in patients with chronic hepatitis B.
Taiyu He, Min Chen, Maoying Liu, Li Zhang, Huidan Sun, Lu Zhang, Aoyi Li, Weiqun Zeng, Ning Ling, Xiaofeng Shi, Hua He, Mingli Peng, Dachuan Cai, Peng Hu, Dazhi Zhang
Published: 202510.1136/gutjnl-2025-336655
Abstract
BACKGROUND: PD-1 blockade has emerged as a promising approach for functional cure of chronic hepatitis B (CHB). OBJECTIVE: This study aimed to evaluate the safety profile of anti-PD-1 antibody (αPD-1), as well as its impact on hepatitis B surface ant…
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