Gut
Targeting cancer stem cells enhances multikinase inhibitor therapy in metabolic dysfunction-associated steatotic liver disease-related hepatocellular carcinoma.
Yasi Pan, Xiang Zhang, Chi Chun Wong, Huarong Chen, Stephanie Ma, Terence Kin-Wah Lee, Kai Yuan, Cong Liang, Xingyu Zhou, Harry Cheuk Hay Lau, Pingmei Huang, Danyu Chen, Lina Wang, Yanqiang Ding, Qinyao Wei
Published: 202510.1136/gutjnl-2025-336527
Abstract
OBJECTIVE: Metabolic dysfunction-associated steatotic liver disease-related hepatocellular carcinoma (MASLD-HCC) is an emerging malignancy with limited therapeutic options. The identity and function of cancer stem cells (CSCs) in MASLD-HCC remain poo…
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