GutAnimalsLipid DropletsHumansNanoparticlesMice
Discovery of a carboxyl fullerene derivative as a new lipid droplet regulator inhibiting MASLD.
Toujun Zou, Juan Wan, Rufang Liao, Lan Bai, Xinyan Li, Xu Cheng, Junjie Zhou, Qinchao Tang, Yufeng Zhang, Chong Zhao, Weiyi Qu, Jinjie Yang, Xiang Zhang, Tian Tian, Xinxin Yao
Published: 202610.1136/gutjnl-2025-336268
Abstract
BACKGROUND: The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) is rapidly increasing with high risk to develop cirrhosis, hepatocellular carcinoma (HCC) and other end-stage liver diseases. However, only two drugs, resm…
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