BMJ case reportsHumansLung NeoplasmsGranulocyte Colony-Stimulating FactorProtein-Tyrosine KinasesCarcinoma
Profound neutrophilia as the presenting sign of GCSF-secreting, ROS1-mutant squamous cell lung cancer.
Sahil Garg, Amol Dua, Adam Rock
Published: 202510.1136/bcr-2025-267778
Abstract
This is a case of squamous cell cancer (SCC) of the lung masquerading as a haematologic malignancy with marked neutrophilia ultimately found to have a ROS1 rearrangement in a non-smoker patient. The patient achieved a near complete response to therap…
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