Microbiology spectrum
Bidirectional relationship between the biofilm of Porphyromonas gingivalis and the amyloid-beta peptide.
David Dumoulin, Mnar Ghrayeb, Sarah Côté, Daniel Garneau, Liraz Chai, Eric H Frost, Tamàs Fülöp, Pascale B Beauregard
Published: 202610.1128/spectrum.01981-25
Abstract
Periodontitis and Porphyromonas gingivalis infections are significant risk factors for the onset of Alzheimer's disease (AD). Despite the reliance of P. gingivalis on its biofilm for its survival and virulence, the impact of the extracellular matrix…
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