Microbiology spectrum
A sequence-specific, nanoparticle-based biosensor platform for rapid and visual identification of serum hepatitis B virus pregenomic RNA in chronic hepatitis B patients.
Yuanyuan Gu, Qi Zhao, Yan Tan, Junfei Huang, Yi Wang, Shijun Li, Xu Chen
Published: 202510.1128/spectrum.01918-25
Abstract
Chronic hepatitis B virus (HBV) infection is a major cause of liver-related morbidity and mortality worldwide. Serum HBV pregenomic RNA (pgRNA) is a surrogate marker for the transcriptional activity of covalently closed circular DNA. Here, we success…
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