Microbiology spectrum
Monocolonization with Bacteroides thetaiotaomicron exerts region-specific effects on Alzheimer's disease-related traits in the murine brain.
Vu Thu Thuy Nguyen, Svenja König, Henning Formes, Zukaa Al Taleb, Florian Steinert, Bernd Bufe, Simone Eggert, Simone Stegmüller, Yannik Schermer, Elke Richling, Stefan Kins, Christoph Reinhardt, Kristina Endres
Published: 202610.1128/spectrum.00744-25
Abstract
Bacteroides thetaiotaomicron (B. theta) dominates the gut microbiome of most mammals. This strictly anaerobic gut symbiont colonizes the mucus layer of host intestinal epithelial cells in both healthy and diseased conditions. Reduced neuronal and vag…
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