Microbiology resource announcements
PDIM/PGL-deficient Mycobacterium marinum shows disrupted protein secretion measured with bottom-up label-free quantitative analysis in data-dependent acquisition mode on a timsTOF Pro 2 mass spectrometer.
Simon D Weaver, Daniel D Hu, Bradley S Jones, Patricia A Champion, Matthew M Champion
Published: 202510.1128/mra.01161-25
Abstract
We investigated the chemical and functional consequences of a Mycobacterium marinum strain deficient in phthiocerol dimycocerosate and phenolic glycolipid (PDIM/PGL) virulence lipids using quantitative proteomics. The significant dysregulation of 1,0…
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