Depth-resolved paired metagenomes and metatranscriptomes from the Lake Erie 'dead zone'.

Metagenomes and metatranscriptomes were generated from the surface mixed layer and hypolimnion at a NOAA-Great Lakes Environmental Research Laboratory Real-Time Coastal Observation Network (ReCON) site in Lake Erie's central basin during the onset of hypolimnetic hypoxia. Here, we describe the sequencing of the samples, metagenome assembly, and binning of microbial taxa.