16S rRNA gene amplicon sequences from coastal sediments at the Sonoran Desert and Gulf of California interface.

We report the taxonomic composition of bacterial and archaeal communities from sand and salt-crust sediments in the coastal Sonoran Desert, Mexico. Analysis of 16S rRNA gene amplicon sequences revealed Halobacterota, Bacteroidota, and Proteobacteria as dominant phyla, providing a resource to explore microbial diversity in extreme environments.