mBio
A new mouse model of typhoid fever using Salmonella enterica serovar Paratyphi C as a surrogate pathogen.
Hoan T Pham, Masatomo Morita, Kohei Yamazaki, Toshihiro Endo, Satoshi Takayama, Azusa Hiyoshi, Takeshi Haneda, Renée M Tsolis, Andreas J Bäumler, Toshio Kodama, Hirotaka Hiyoshi
Published: 202610.1128/mbio.03622-25
Abstract
Salmonella enterica serovar (S.) Typhi, the etiological agent of typhoid fever, is strictly human adapted, which presents a significant challenge for studying its pathogenesis in animal models. A common strategy to overcome this limitation is to infe…
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