mBio
The C-terminus of infectious bursal disease virus VP3 encodes a predicted intrinsically disordered region, which promotes the formation of cytoplasmic puncta and modulates their physical properties.
A J Brodrick, M Liu, G Smith-Hicks, J Dong, S C Egana-Labrin, A J Broadbent
Published: 202610.1128/mbio.03107-25
Abstract
The virus factories (VFs) of infectious bursal disease virus (IBDV) are biomolecular condensates formed through liquid-liquid phase separation (LLPS). A major component of the IBDV VF is the nonstructural protein VP3, but the molecular basis underlyi…
Preview only. Read the full abstract at the source