Journal of virology
MPXV RNA-seq data provide evidence for protection of viral transcripts from APOBEC3 editing.
Alisa O Lyskova, Ruslan Kh Abasov, Anna Pavlova, Evgenii V Matveev, Alexandra V Madorskaya, Fedor M Kazanov, Daria V Garshina, Anna E Smolnikova, Gennady V Ponomarev, Elena I Sharova, Dmitry N Ivankov, Ogun Adebali, Mikhail S Gelfand, Marat D Kazanov
Published: 202610.1128/jvi.02082-25
Abstract
The 2022 outbreak of monkeypox virus (MPXV), a double-stranded DNA virus, is remarkable for an unusually high number of single-nucleotide substitutions compared to earlier strains, with a strong bias toward C→T and G→A transitions consistent with the…
Preview only. Read the full abstract at the source