Antimicrobial agents and chemotherapy
Essential role of MHC II in the antitubercular efficacy of pyrazinamide.
Elise A Lamont, Shannon L Kordus, Michael D Howe, Ziyi Jia, Nathan Schacht, Muzafar Ahmad Rather, Gebremichal Gebretsadik, Anthony D Baughn
Published: 202510.1128/aac.01264-25
Abstract
Antibacterial drug mechanisms have traditionally been examined through a drug-pathogen lens, with limited attention to host influences on drug activity. However, growing evidence suggests that the host environment is crucial for antibacterial efficac…
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