Science translational medicineAnimalsHumansCandidiasisInvasiveDisease Models
Meteorin-like is associated with poor outcome in invasive candidiasis in mouse models and in humans.
Jiayu Liu, Hao Ding, Wang Tan, Renlin Yu, Yue Li, Yuhan Liu, Mengxue Liu, Ping Zhao, Yi Liu, Fang Xu, Xiaofei Lai, Ju Cao
Published: 202610.1126/scitranslmed.adw8481
Abstract
Invasive candidiasis is a leading cause of nosocomial bloodstream infection associated with high mortality, and there is a pressing need to develop biomarker-guided antifungal therapy to improve clinical outcomes. Meteorin-like (METRNL) is a cytokine…
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