Science translational medicineHumansGlioblastomaMaleTumor MicroenvironmentBrain Neoplasms
Serial multiomics uncovers anti-glioblastoma responses not evident by routine clinical analyses.
Alexander L Ling, Jennifer Gantchev, Michael C Prabhu, Sreyashi Basu, Ryuhjin Ahn, Alicia D'Souza, Nafisa Masud, Anna Ball, Odysseas Nikas, Genaro R Villa, Michael S Regan, Gerard Baquer, Georges Ayoub, Charles A Whittaker, Zaki Abou-Mrad
Published: 202510.1126/scitranslmed.adv2881
Abstract
Recurrent glioblastoma (rGBM) remains incurable. One barrier to the development of effective rGBM therapies is the difficulty in collecting posttreatment tumor tissue. Serial multiomic assays from longitudinal rGBM biopsies may uncover tumor response…
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