Science translational medicineAnimalsCollagenTissue ScaffoldsRabbitsWound Healing
A bioinspired mineralized collagen scaffold promotes enthesis healing and activates Gli1 expression in preclinical models.
Tao Zhang, Tingyun Lei, Jie Han, Yangwu Chen, Yuepeng Nie, Ru Zhang, Honglu Cai, Zijin Guo, Ruojin Yan, Zan Li, Yongqiang Xu, Xianzhu Zhang, Hongxia Xu, Jiahe Chen, Youguo Liao
Published: 202510.1126/scitranslmed.ado6948
Abstract
The enthesis, a fibrocartilaginous tissue connecting tendon or ligament to bone, is critical for joint movement but lacks regenerative capacity after injury. Current clinical treatments for enthesis healing remain limited. Here, with a resolution of…
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