Science immunologyHumansDendritic CellsInflammatory Bowel DiseasesFemaleMale
Heterogeneity of the intestinal mononuclear phagocyte compartment in health and inflammatory bowel disease.
Thomas M Fenton, Line Wulff, Venla Väänänen, Gareth-Rhys Jones, Camilla Koldbæk Lemvigh, Lene B Riis, Mads Damsgaard Wewer, Julien Vandamme, Peter B Jørgensen, Calum C Bain, Kirstine G Belling, Gwo-Tzer Ho, Tune H Pers, Anja Poulsen, Gorm R Madsen
Published: 202510.1126/sciimmunol.adz8650
Abstract
Understanding of mononuclear phagocyte (MNP) diversity in the human intestine and the alterations this compartment undergoes in inflammation remains incomplete. Here, we used single-cell RNA sequencing, cellular indexing of trancriptomes and epitopes…
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