Science immunologyAnimalsAsthmaRespiratory Syncytial Virus InfectionsFemaleAllergens
Maternal allergy and neonatal RSV infection synergize via FcR-mediated allergen uptake to promote the development of asthma in early life.
Elisabeth De Leeuw, Josefine F Justesen, Cédric Bosteels, Nincy Debeuf, Manon Vanheerswynghels, Leander Jonckheere, Caroline De Wolf, Alysia Wayenberg, Karel F A Van Damme, Stijn Vanhee, Manon Lesage, Kim Deswarte, Sam Dupont, Morten Dahl, Hamida Hammad
Published: 202510.1126/sciimmunol.adz4626
Abstract
Allergic asthma arises from complex genetic and environmental interactions. Analysis of a population-wide registry revealed that infants hospitalized for human respiratory syncytial virus (RSV) bronchiolitis who are born to asthmatic parents have a m…
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