Science immunologyAnimalsFemaleMaleErbB ReceptorsMice
Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen.
Helen Stölting, April L Raftery, Simone A Walker, Eimear N Rutherford, Mindy L Gore, Yue Huang, Franz Puttur, Laura Yates, Sejal Saglani, Clare M Lloyd
Published: 202610.1126/sciimmunol.adk1673
Abstract
Hormonal disruptions are associated with poor asthma control in females, yet how these phenomena are linked remains unknown. Here, we investigated distinct allergen-induced immune responses between the sexes during maturation. By 6 weeks of life, fem…
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