Science (New York, N.Y.)Deep LearningCardiomyopathyHypertrophicAnimalsMyocytes
Deep-learning analysis of 3D microarchitectural remodeling in hypertrophic cardiomyopathy.
Eric Q Wei, Martin Beyer, Kemar J Brown, Alexander J Bansbach, Joshua M Gorham, Barbara McDonough, Huachen Chen, Mobin Khoramjoo, Anran Zhang, Brian Bishop, Ferhaan Ahmad, Carlos Del Rio, Ching-Pin Chang, David M Ryba, Sharlene M Day
Published: 202610.1126/science.ady6443
Abstract
Hypertrophic cardiomyopathy (HCM), a genetic heart disease defined by unexplained cardiac wall thickening, is a leading cause of sudden death worldwide. However, the three-dimensional organization of cardiac tissue underlying left ventricular hypertr…
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