Science (New York, N.Y.)AnimalsHumansCell MembraneExtracellular SpaceMembrane Proteins
Targeted protein degradation in the transmembrane and extracellular space.
Rongfeng Zhu, Heng Zhang, Peng R Chen
Published: 202510.1126/science.adx5094
Abstract
Transmembrane and extracellular proteins play crucial roles in diverse cellular functions and communication, affecting the progression and treatment of various diseases by mediating vital cellular processes. Whereas targeted protein degradation (TPD)…
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