Science (New York, N.Y.)KineticsSingle Molecule ImagingMolecular Dynamics SimulationNucleic Acid ConformationProteins
From sequence to function: Bridging single-molecule kinetics and molecular diversity.
A N Kapanidis, L Muras, K Sreenivasa, J P Hazra, J van Noort, C Joo, S Deindl
Published: 202610.1126/science.adv4503
Abstract
Biological function is fundamentally determined by nucleic acid and protein sequence. Beyond encoding genetic information, nucleic acids also display complex physicochemical parameters that shape structure, dynamics, and interactions. Understanding h…
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