Science (New York, N.Y.)AnimalsFemaleMiceCD8-Positive T-LymphocytesEpithelial Cells
Rebalancing viral and immune damage versus repair prevents death from lethal influenza infection.
Hiroshi Ichise, Emily Speranza, Federica La Russa, Tibor Z Veres, Colin J Chu, Anita Gola, Beatrice H Clark, Ronald N Germain
Published: 202510.1126/science.adr4635
Abstract
Maintaining tissue function while eliminating infected cells is fundamental, and inflammatory damage plays a major contribution to lethality after lung infection. We tested 50 immunomodulatory regimes to determine their ability to protect mice from l…
Preview only. Read the full abstract at the source