Science advancesAnimalsMiceMalariaPlasmodium chabaudiMycobacterium tuberculosis
From Plato to Pareto: Defining the shape of infection's disease space.
Yael Lebel, Avni S Gupta, Victoria Chevée, Uri Alon, David S Schneider
Published: 202610.1126/sciadv.aeb3911
Abstract
If the immune system is an interconnected network, then the evolution of an archetype that is ideal for fighting one pathogen should result in trade-offs decreasing its ability to fight others. How many archetypes are there in an immune system? We in…
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